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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280)   

ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280)

Rabbit Polyclonal Antibody

  • IHC - ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280) ALS16725
    Huma Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280) ALS16725
    Anti-ADCY1 / Adenylate Cyclase 1 antibody IHC staining of human brain, cortex.
  • WB - ADCY1 / Adenylate Cyclase 1 Antibody (aa231-280) ALS16725
    Western blot of extracts from COLO205 cells, using ADCY1 Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08828
Other Accession 107
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 123440 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 107
Other Names ADCY1, 3, 5-cyclic AMP synthetase, Adenylate cyclase type I, AC1, Adenylate cyclase type 1, Adenylyl cyclase 1, ATP pyrophosphate-lyase 1, Adenyl cyclase, Adenylate cyclase 1 (brain), Adenylate cyclase, type i, ATP pyrophosphate-lyase
Target/Specificity ADCY1 Antibody detects endogenous levels of total ADCY1 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsADCY1 / Adenylate Cyclase 1 Antibody (aa231-280) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCY1
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels (By similarity). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P19754}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P19754}. Cell membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:O88444} Membrane raft {ECO:0000250|UniProtKB:P19754}. Note=Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia. {ECO:0000250|UniProtKB:O88444}
Tissue Location Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Brain, retina and adrenal medulla
Volume 50 µl
Research Areas
Citations (0)

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This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).


Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Villacres E.C.,et al.Genomics 16:473-478(1993).
Santos-Cortez R.L.,et al.Hum. Mol. Genet. 23:3289-3298(2014).

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$ 395.00
Cat# ALS16725
Availability: 5 days
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