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TMEM30B Antibody (aa91-140)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q3MIR4 |
| Other Accession | 161291 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 38941 Da |
| Dilution | ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 161291 |
|---|---|
| Other Names | TMEM30B, CDC50B, Cell cycle control protein 50B, Transmembrane protein 30B |
| Target/Specificity | TMEM30B Antibody detects endogenous levels of total TMEM30B protein. |
| Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
| Precautions | TMEM30B Antibody (aa91-140) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMEM30B |
|---|---|
| Synonyms | CDC50B |
| Function | Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Katoh Y.,et al.Oncol. Rep. 12:939-943(2004).
van der Velden L.M.,et al.J. Biol. Chem. 285:40088-40096(2010).
Bryde S.,et al.J. Biol. Chem. 285:40562-40572(2010).
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