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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TMEM30B Antibody (aa91-140)   

TMEM30B Antibody (aa91-140)

Rabbit Polyclonal Antibody

     
  • IHC - TMEM30B Antibody (aa91-140) ALS16726
    Anti-TMEM30B antibody IHC staining of human adrenal.
  • WB - TMEM30B Antibody (aa91-140) ALS16726
    Western blot of extracts from K562 cells, using TMEM30B Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q3MIR4
Other Accession 161291
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38941 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 161291
Other Names TMEM30B, CDC50B, Cell cycle control protein 50B, Transmembrane protein 30B
Target/Specificity TMEM30B Antibody detects endogenous levels of total TMEM30B protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsTMEM30B Antibody (aa91-140) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM30B
Synonyms CDC50B
Function Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
Cellular Location Cell membrane; Multi-pass membrane protein
Volume 50 µl
Research Areas
Citations (0)

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Background

Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Katoh Y.,et al.Oncol. Rep. 12:939-943(2004).
van der Velden L.M.,et al.J. Biol. Chem. 285:40088-40096(2010).
Bryde S.,et al.J. Biol. Chem. 285:40562-40572(2010).

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$ 395.00
Cat# ALS16726
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