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CCL4 / SYCA4 Antibody (Internal)
Rabbit Polyclonal Antibody
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Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P13236 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 10212 Da |
| Dilution | IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml), |
| Gene ID | 388372;6351 |
|---|---|
| Other Names | C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta(1-69), Macrophage inflammatory protein 1-beta, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP-1-beta(3-69), CCL4, LAG1, MIP1B, SCYA4 |
| Target/Specificity | Human CCL4 / SYCA4 |
| Reconstitution & Storage | PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CCL4 / SYCA4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCL4 |
|---|---|
| Synonyms | LAG1, MIP1B, SCYA4 |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1- beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Cellular Location | Secreted. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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