|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||18648 Da|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||CNRIP1, C2orf32, CRIP-1, CRIP1a, CRIP1b, DKFZP566K1924|
|Target/Specificity||At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CNRIP1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect.
Niehaus J.L.,et al.Mol. Pharmacol. 72:1557-1566(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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