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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   ERAP2 / Aminopeptidase Antibody (N-Terminus)   

ERAP2 / Aminopeptidase Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ERAP2 / Aminopeptidase Antibody (N-Terminus) ALS16771
    Anti-ERAP2 / Aminopeptidase antibody IHC staining of human kidney.
  • IHC - ERAP2 / Aminopeptidase Antibody (N-Terminus) ALS16771
    Anti-ERAP2 / Aminopeptidase antibody IHC staining of human liver.
  • IF - ERAP2 / Aminopeptidase Antibody (N-Terminus) ALS16771
    Immunofluorescence of ERAP2 in rat small intestine tissue with ERAP2 antibody at 5 ug/ml.
  • WB - ERAP2 / Aminopeptidase Antibody (N-Terminus) ALS16771
    Western blot analysis of ERAP2 in rat small intestine tissue lysate with ERAP2 antibody at 1 ug/ml.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q6P179
Other Accession 64167
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 110462 Da
Dilution IF (5 µg/ml), IHC-P (10 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 64167
Other Names ERAP2, Aminopeptidase, L-RAP, LRAP
Target/Specificity ERAP2 antibody is human, mouse and rat reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsERAP2 / Aminopeptidase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERAP2
Synonyms LRAP
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Ubiquitously expressed. Highly expressed in spleen and leukocytes.
Research Areas
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Background

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.

References

Tanioka T.,et al.J. Biol. Chem. 278:32275-32283(2003).
Tanioka T.,et al.FEBS J. 272:916-928(2005).
Schomburg L.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).

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$ 395.00
Cat# ALS16771
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