|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||34455 Da|
|Dilution||IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||THAP11, CTG-B45d, HRIHFB2206, RONIN, THAP domain containing 11, CTG-B43a|
|Target/Specificity||THAP11 antibody is human, mouse and rat reactive.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CTG-B45d / THAP11 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Santana-Roman H.,et al.Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
Ueki N.,et al.Nat. Biotechnol. 16:1338-1342(1998).
Pandey N.,et al.J. Hum. Genet. 49:596-602(2004).
Gervais V.,et al.J. Biomol. NMR 56:3-15(2013).
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