|Application ||WB, IHC-P, ICC|
|Calculated MW||21604 Da|
|Dilution||ICC (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:500 - 1:3000),|
|Other Names||HSPB8, Alpha-crystallin C chain, CMT2L, Crystallin alpha c, DHMN2, E2-induced gene 1 protein, CRYAC, E2IG1, HMN2, H11, Heat shock 27kDa protein 8, Heat shock protein beta-8, Heat shock 22kDa protein 8, HMN2A, HSP22, Protein kinase H11|
|Target/Specificity||Human HSPB8 / H11 / HSP22|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||HSPB8 / H11 / HSP22 Antibody (aa134-196) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CRYAC, E2IG1, HSP22|
|Function||Displays temperature-dependent chaperone activity.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock|
|Tissue Location||Predominantly expressed in skeletal muscle and heart.|
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Provided below are standard protocols that you may find useful for product applications.
Displays temperature-dependent chaperone activity.
Charpentier A.H.,et al.Cancer Res. 60:5977-5983(2000).
Benndorf R.,et al.J. Biol. Chem. 276:26753-26761(2001).
Smith C.C.,et al.J. Biol. Chem. 275:25690-25699(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
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