|Application ||WB, IHC-P, ICC|
|Calculated MW||21604 Da|
|Dilution||ICC (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:500 - 1:3000),|
|Other Names||HSPB8, Alpha-crystallin C chain, CMT2L, Crystallin alpha c, DHMN2, E2-induced gene 1 protein, CRYAC, E2IG1, HMN2, H11, Heat shock 27kDa protein 8, Heat shock protein beta-8, Heat shock 22kDa protein 8, HMN2A, HSP22, Protein kinase H11|
|Target/Specificity||Human HSPB8 / H11 / HSP22|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||HSPB8 / H11 / HSP22 Antibody (aa134-196) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CRYAC, E2IG1, HSP22|
|Function||Displays temperature-dependent chaperone activity.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock|
|Tissue Location||Predominantly expressed in skeletal muscle and heart.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Displays temperature-dependent chaperone activity.
Charpentier A.H.,et al.Cancer Res. 60:5977-5983(2000).
Benndorf R.,et al.J. Biol. Chem. 276:26753-26761(2001).
Smith C.C.,et al.J. Biol. Chem. 275:25690-25699(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
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