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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   INPP5K / SKIP Antibody (aa183-430)   

INPP5K / SKIP Antibody (aa183-430)

Rabbit Polyclonal Antibody

     
  • IHC - INPP5K / SKIP Antibody (aa183-430) ALS16802
    Anti-INPP5K / SKIP antibody IHC staining of human skeletal muscle.
  • IHC - INPP5K / SKIP Antibody (aa183-430) ALS16802
    Anti-INPP5K / SKIP antibody IHC staining of human uterus.
  • IHC - INPP5K / SKIP Antibody (aa183-430) ALS16802
    immunohistochemical staining of formalin - fixed paraffin-embedded fetal skeletal
  • WB - INPP5K / SKIP Antibody (aa183-430) ALS16802
    wester blot analysis of fetal heart lysate with anti-inpp5k antibody
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BT40
Other Accession 51763
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 51090 Da
Dilution ELISA (1:20000 - 1:80000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 51763
Other Names INPP5K, SKIP, PPS
Target/Specificity Human INPP5K / SKIP.
Reconstitution & Storage PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year.
PrecautionsINPP5K / SKIP Antibody (aa183-430) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INPP5K
Synonyms PPS, SKIP
Function Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton.
Cellular Location Endoplasmic reticulum. Note=Following stimulation with EGF, translocates to membrane ruffles
Tissue Location Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
Research Areas
Citations (0)

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Background

Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton.

References

Ijuin T.,et al.J. Biol. Chem. 275:10870-10875(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Nussbaum R.L.,et al.Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
Gurung R.,et al.J. Biol. Chem. 278:11376-11385(2003).

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$ 395.00
Cat# ALS16802
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