|Application ||WB, IHC-P, E|
|Calculated MW||70109 Da|
|Dilution||ELISA (10 µg/ml), IHC-P (5 µg/ml), WB (10 µg/ml),|
|Other Names||F11, Coagulation factor XI, Factor xi deficiency, F11 deficiency, Factor XI, PTA deficiency, PTA, Rosenthal syndrome, FXI|
|Target/Specificity||Recognizes human Factor XI.|
|Reconstitution & Storage||ddH20, 50% glycerol. May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.|
|Precautions||F11 / FXI / Factor XI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.|
|Tissue Location||Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Fujikawa K.,et al.Biochemistry 25:2417-2424(1986).
Asakai R.,et al.Biochemistry 26:7221-7228(1987).
Hsu T.-C.,et al.J. Biol. Chem. 273:13787-13793(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.