THNSL2 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q86YJ6 |
Other Accession | 55258 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 54116 Da |
Dilution | ELISA (1:128000), IHC-P (5 µg/ml), |
Gene ID | 55258 |
---|---|
Other Names | THNSL2, Threonine synthase-like 2, THS2, TSH2, SOFAT |
Target/Specificity | Human THNSL2. This antibody is expected to recognize isoform 1 (NP_060741.3) and isoform 2 (NP_001231605.1) only. |
Reconstitution & Storage | Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
Precautions | THNSL2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THNSL2 |
---|---|
Function | [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). |
Cellular Location | [Isoform SOFAT]: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway |
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Provided below are standard protocols that you may find useful for product applications.
Background
Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).
References
Rifas L.,et al.Arthritis Rheum. 60:3324-3335(2009).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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