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CORO1A / Coronin 1a Antibody

Rabbit Polyclonal Antibody

     
  • IHC - CORO1A / Coronin 1a Antibody ALS16830
    Anti-CORO1A / p57 antibody IHC staining of human spleen.
  • ICC - CORO1A / Coronin 1a Antibody ALS16830
    Immunocytochemistry of a mixed neuron/glial culture from newborn rat brain stained with CORO1A /...
  • WB - CORO1A / Coronin 1a Antibody ALS16830
    Western blot of HL60 cell extract stained with CORO1A / p57 antibody, at dilution of 1:10,000.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession P31146
Other Accession 11151
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 51026 Da
Dilution ICC (1:5000), IF (1:500 - 1:1000), IHC-P (1:100), WB (1:20000),
Additional Information
Gene ID 11151
Other Names CORO1A, Clipin-A, Coronin-like protein A, Coronin-like protein p57, CLIPINA, Coronin-1, Coronin-1A, HCORO1, p57, TACO, CLABP, CORO1
Target/Specificity Human CORO1A / p57
Reconstitution & Storage Antiserum. +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsCORO1A / Coronin 1a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CORO1A
Synonyms CORO1
Function May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle, phagosome membrane. Note=In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity).
Tissue Location Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut
Volume 50 µl
Research Areas
Citations (0)

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Background

May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.

References

Suzuki K.,et al.FEBS Lett. 364:283-288(1995).
Grogan A.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Liau G.,et al.Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases.
Kohchi C.,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16830
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