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Fibulin-3 / EFEMP1 Antibody (clone 1D9)

Mouse Monoclonal Antibody

     
  • IHC - Fibulin-3 / EFEMP1 Antibody (clone 1D9) ALS16834
    Anti-Fibulin-3 / EFEMP1 antibody IHC staining of human testis.
  • WB - Fibulin-3 / EFEMP1 Antibody (clone 1D9) ALS16834
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EFEMP1...
  • FC - Fibulin-3 / EFEMP1 Antibody (clone 1D9) ALS16834
    Flow cytometry of Jurkat cells, using anti-EFEMP1 antibody (Red), compared to a nonspecific...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, Flo
Primary Accession Q12805
Other Accession 2202
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 1D9
Calculated MW 54641 Da
Dilution Flo (1:100), IHC-P (10 µg/ml), WB (1:200 - 1:500),
Additional Information
Gene ID 2202
Other Names EFEMP1, DHRD, Extracellular protein S1-5, FBNL, FBLN3, Fibrillin-like protein, Fibrillin-like, MLVT, S1-5, MTLV, DRAD, FIBL-3, Fibulin-3
Target/Specificity Human Fibulin-3 / EFEMP1
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsFibulin-3 / EFEMP1 Antibody (clone 1D9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFEMP1
Synonyms FBLN3, FBNL
Function Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Cellular Location Secreted, extracellular space. Secreted, extracellular space, extracellular matrix Note=Localizes to the lamina propria underneath the olfactory epithelium.
Tissue Location In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina
Volume 50 µl
Research Areas
Citations (0)

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Background

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

References

Lecka-Czernik B.,et al.Mol. Cell. Biol. 15:120-128(1995).
Ikegawa S.,et al.Genomics 35:590-592(1996).
Giltay R.,et al.Matrix Biol. 18:469-480(1999).
Sauer C.G.,et al.Ophthalmic Genet. 22:27-34(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16834
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