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FOXI3 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - FOXI3 Antibody (Internal) ALS16836
    Huhuman Bronchus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession A8MTJ6
Other Accession 344167
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 43326 Da
Dilution IHC-P (5 µg/ml),
Additional Information
Gene ID 344167
Other Names FOXI3, Forkhead box protein I3, Forkhead box I3
Target/Specificity Human FOXI3.
Reconstitution & Storage Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsFOXI3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXI3 {ECO:0000303|PubMed:36260083, ECO:0000312|HGNC:HGNC:35123}
Function Transcription factor required for pharyngeal arch development, which is involved in hair, ear, jaw and dental development (PubMed:37041148). May act as a pioneer transcription factor during pharyngeal arch development (By similarity). Required for epithelial cell differentiation within the epidermis (By similarity). Acts at multiple stages of otic placode induction: necessary for preplacodal ectoderm to execute an inner ear program (By similarity). Required for hair follicle stem cell specification (By similarity). Acts downstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch (By similarity).
Cellular Location Nucleus.
Citations (0)
citation

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Background

Possible transcriptional factor.

References

Hillier L.W.,et al.Nature 434:724-731(2005).
Droegemueller C.,et al.Science 321:1462-1462(2008).

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Discontinued
Cat# ALS16836
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