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TNFSF12 / TWEAK Antibody (Pro73)

Rabbit Polyclonal Antibody

     
  • IHC - TNFSF12 / TWEAK Antibody (Pro73) ALS16844
    Anti-TNFSF12 / TWEAK antibody IHC staining of human heart.
    detail
  • IHC - TNFSF12 / TWEAK Antibody (Pro73) ALS16844
    Anti-TNFSF12 / TWEAK antibody IHC staining of human small intestine.
    detail
  • IHC - TNFSF12 / TWEAK Antibody (Pro73) ALS16844
    IHC of TWEAK (P73) pAb in paraffin-embedded human brain tissue.
    detail
  • WB - TNFSF12 / TWEAK Antibody (Pro73) ALS16844
    Western blot of TWEAK (P73) pAb in extracts from COLO cells.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IHC-P, IF
Primary Accession O43508
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 27216 Da
Dilution IHC (1:50 - 1:200), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 407977;8742
Other Names Tumor necrosis factor ligand superfamily member 12, APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12, APO3L, DR3LG
Target/Specificity Human TWEAK
Reconstitution & Storage PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsTNFSF12 / TWEAK Antibody (Pro73) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF12
Synonyms APO3L, DR3LG
Function Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Cellular Location Cell membrane; Single-pass type II membrane protein [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein
Tissue Location Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain
Volume 50 µl
Research Areas
Citations (0)
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Discontinued
Cat# ALS16844
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