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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PSAT1 Antibody (aa48-328)   

PSAT1 Antibody (aa48-328)

Rabbit Polyclonal Antibody

     
  • IHC - PSAT1 Antibody (aa48-328) ALS16845
    Anti-PSAT1 antibody IHC staining of human kidney.
    detail
  • ICC - PSAT1 Antibody (aa48-328) ALS16845
    Immunofluorescence of paraformaldehyde-fixed A549 using PSAT1 antibody at 1:200 dilution.
    detail
  • WB - PSAT1 Antibody (aa48-328) ALS16845
    Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. PSAT1 antibody diluted at 1:1000
    detail
  • WB - PSAT1 Antibody (aa48-328) ALS16845
    Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. PSAT1 antibody diluted at 1:1000.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q9Y617
Other Accession 29968
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 40423 Da
Dilution ICC (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:500 - 1:3000),
Additional Information
Gene ID 29968
Other Names PSAT1, EPIP, Phosphoserine aminotransferase, PSA, PSAT
Target/Specificity Human PSAT1
Reconstitution & Storage 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsPSAT1 Antibody (aa48-328) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSAT1 (HGNC:19129)
Synonyms PSA
Function Involved in L-serine biosynthesis via the phosphorylated pathway, a three-step pathway converting the glycolytic intermediate 3- phospho-D-glycerate into L-serine. Catalyzes the second step, that is the pyridoxal 5'-phosphate-dependent transamination of 3- phosphohydroxypyruvate and L-glutamate to O-phosphoserine (OPS) and alpha-ketoglutarate.
Tissue Location Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Research Areas
Citations (0)
citation

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Background

Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.

References

Baek J.Y.,et al.Biochem. J. 373:191-200(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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Discontinued
Cat# ALS16845
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