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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PFDN5 / MM1 Antibody   

PFDN5 / MM1 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - PFDN5 / MM1 Antibody ALS16854
    Anti-PFDN5 / MM1 antibody IHC staining of human pancreas.
  • WB - PFDN5 / MM1 Antibody ALS16854
    Western blot of Prefoldin subunit 5 antibody at 2 ug/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99471
Other Accession 5204
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 17328 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 5204
Other Names PFDN5, C-Myc-binding protein Mm-1, C-myc binding protein, MM-1, Myc modulator 1, Myc modulator-1, Prefoldin 5, MM1, PFD5, Prefoldin subunit 5
Target/Specificity Human PFDN5 / MM1
Reconstitution & Storage PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
PrecautionsPFDN5 / MM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PFDN5
Synonyms MM1, PFD5
Function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Cellular Location Isoform 1: Nucleus. Isoform 3: Nucleus.
Tissue Location Highly expressed in pancreas and skeletal muscle and moderately in other tissues
Research Areas
Citations (0)

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Background

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.

References

Mori K.,et al.J. Biol. Chem. 273:29794-29800(1998).
Fujioka Y.,et al.J. Biol. Chem. 276:45137-45144(2001).
Hagio Y.,et al.J. Cell. Biochem. 97:145-155(2006).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16854
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