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ASS1 / ASS Antibody (clone 2B10)

Mouse Monoclonal Antibody

     
  • IHC - ASS1 / ASS Antibody (clone 2B10) ALS16870
    Anti-ASS1 / ASS antibody IHC staining of human kidney.
    detail
  • IF - ASS1 / ASS Antibody (clone 2B10) ALS16870
    Immunofluorescence of HeLa cells using ASS1 mouse monoclonal antibody (green).
    detail
  • WB - ASS1 / ASS Antibody (clone 2B10) ALS16870
    Western blot using ASS1 monoclonal antibody against human ASS1 (AA: 40-236) recombinant protein.
    detail
  • WB - ASS1 / ASS Antibody (clone 2B10) ALS16870
    Western blot using ASS1 mouse monoclonal antibody against A431 (1), RAJI (2), L1210 (3), MOLT4...
    detail
  • E - ASS1 / ASS Antibody (clone 2B10) ALS16870
    Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, E, Flo
Primary Accession P00966
Other Accession 445
Reactivity Human, Mouse, Rat, Monkey
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2B10
Calculated MW 46530 Da
Dilution ELISA (1:10000), Flo (1:200 - 1:400), ICC (1:200 - 1:1000), IHC-P (10 µg/ml), WB (1:500 - 1:2000),
Additional Information
Gene ID 445
Other Names ASS1, Argininosuccinate synthetase, ASS, Argininosuccinate synthase 1, CTLN1, Citrulline--aspartate ligase, Citrulline-aspartate ligase, Argininosuccinate synthase, Argininosuccinate synthetase 1
Target/Specificity Human ASS1 / ASS
Reconstitution & Storage PBS, 0.05% sodium azide, 0.5% protein stabilizer. Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsASS1 / ASS Antibody (clone 2B10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASS1 (HGNC:758)
Function One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Cellular Location Cytoplasm, cytosol
Tissue Location Expressed in adult liver.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Is indirectly involved in the control of blood pressure.

References

Bock H.-G.O.,et al.Nucleic Acids Res. 11:6505-6512(1983).
Freytag S.O.,et al.J. Biol. Chem. 259:3160-3166(1984).
Haeberle J.,et al.Hum. Genet. 110:327-333(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Jinno Y.,et al.J. Inherit. Metab. Dis. 8:157-159(1985).

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Discontinued
Cat# ALS16870
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