|Application ||WB, IHC-P, ICC|
|Calculated MW||43296 Da|
|Dilution||ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:1000 - 1:10000),|
|Other Names||PDHA1, PDHCE1A, PDHA, PHE1A, PDHE1-A type I|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||PDHA1 / PDH E1 Alpha Antibody (aa39-325) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.|
|Cellular Location||Mitochondrion matrix.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Koike K.,et al.Gene 93:307-311(1990).
Ho L.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5330-5334(1989).
Huh T.L.,et al.Submitted (APR-1990) to the EMBL/GenBank/DDBJ databases.
Dahl H.-H.M.,et al.J. Biol. Chem. 262:7398-7403(1987).
Maragos C.,et al.J. Biol. Chem. 264:12294-12298(1989).
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