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>   home   >   Products   >   Primary Antibodies   >   UFD2A / UBE4B Antibody (aa869-1179)   

UFD2A / UBE4B Antibody (aa869-1179)

Rabbit Polyclonal Antibody

     
  • IHC - UFD2A / UBE4B Antibody (aa869-1179) ALS16888
    Anti-UFD2A / UBE4B antibody IHC staining of human brain, cortex.
  • ICC - UFD2A / UBE4B Antibody (aa869-1179) ALS16888
    Immunofluorescence of methanol-fixed Hep3B using UBE4B antibody at 1:500 dilution.
  • WB - UFD2A / UBE4B Antibody (aa869-1179) ALS16888
    Sample (30 ug of whole cell lysate).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession O95155
Other Accession 10277
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 146185 Da
Dilution ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:5000 - 1:20000),
Additional Information
Gene ID 10277
Other Names UBE4B, KIAA0684, HDNB1, Homologous to yeast UFD2, UFD2, UFD2A, Ubiquitination factor E4B, UBOX3, E4
Target/Specificity Human UFD2A / UBE4B
Reconstitution & Storage 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsUFD2A / UBE4B Antibody (aa869-1179) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE4B (HGNC:12500)
Function Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9ES00}. Nucleus {ECO:0000250|UniProtKB:Q9ES00}
Tissue Location Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen
Volume 50 µl
Citations (0)

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Background

Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase.

References

Onyango P.,et al.Genomics 50:187-198(1998).
Ohira M.,et al.Oncogene 19:4302-4307(2000).
Mahoney J.A.,et al.Biochem. J. 361:587-595(2002).
Mammen A.L.,et al.PLoS ONE 6:E28861-E28861(2011).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).

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$ 395.00
Cat# ALS16888
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