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RAB6A / RAB6 Antibody (aa1-208)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, ICC |
|---|---|
| Primary Accession | P20340 |
| Other Accession | 5870 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 23593 Da |
| Dilution | ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:500 - 1:3000), |
| Gene ID | 5870 |
|---|---|
| Other Names | RAB6A, Rab GTPase, Rab-6, RAB6, Ras-related protein rab-6, RAB6A', Ras-related protein Rab-6A |
| Target/Specificity | Human RAB6 |
| Reconstitution & Storage | 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
| Precautions | RAB6A / RAB6 Antibody (aa1-208) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAB6A |
|---|---|
| Synonyms | RAB6 |
| Function | Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER) (PubMed:25962623). Has a low GTPase activity (PubMed:25962623). Recruits VPS13B to the Golgi membrane (PubMed:25492866). Plays a role in neuron projection development (Probable). |
| Cellular Location | Golgi apparatus membrane; Lipid- anchor. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P35279}; Peripheral membrane protein. Note=BICD2 facilitates its targeting to Golgi apparatus membrane. [Isoform 2]: Golgi apparatus membrane; Lipid-anchor |
| Tissue Location | Ubiquitous.. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
References
Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Caillol N.,et al.J. Cell. Biochem. 79:628-647(2000).
Shan J.,et al.Gene 257:67-75(2000).
Echard A.,et al.Mol. Biol. Cell 11:3819-3833(2000).
Barr F.A.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
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