|Application ||WB, IHC-P, ICC|
|Calculated MW||43665 Da|
|Dilution||ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:500 - 1:3000),|
|Other Names||KRR1, HIV-1 Rev binding protein 2, HIV-1 Rev-binding protein 2, Rev-interacting protein 1, Rev interacting protein, RIP-1, HRB2|
|Target/Specificity||Human RIP-1 / KRR1|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||KRR1 Antibody (aa47-344) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).|
|Cellular Location||Cytoplasm. Nucleus, nucleolus. Note=Translocates from cytoplasm to nucleus after exposure to HIV- 1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).
Ma Z.F.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
D'Sa-Eipper C.,et al.Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (AUG-2005) to UniProtKB.
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