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KRR1 Antibody (aa47-344)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, ICC |
|---|---|
| Primary Accession | Q13601 |
| Other Accession | 11103 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 43665 Da |
| Dilution | ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:500 - 1:3000), |
| Gene ID | 11103 |
|---|---|
| Other Names | KRR1, HIV-1 Rev binding protein 2, HIV-1 Rev-binding protein 2, Rev-interacting protein 1, Rev interacting protein, RIP-1, HRB2 |
| Target/Specificity | Human RIP-1 / KRR1 |
| Reconstitution & Storage | 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
| Precautions | KRR1 Antibody (aa47-344) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRR1 (HGNC:5176) |
|---|---|
| Synonyms | HRB2 |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. |
| Cellular Location | Nucleus, nucleolus |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).
References
Ma Z.F.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
D'Sa-Eipper C.,et al.Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (AUG-2005) to UniProtKB.
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