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>   home   >   Products   >   Primary Antibodies   >   RNF114 / ZNF313 Antibody (aa1-228)   

RNF114 / ZNF313 Antibody (aa1-228)

Rabbit Polyclonal Antibody

     
  • IHC - RNF114 / ZNF313 Antibody (aa1-228) ALS16904
    Anti-RNF114 / ZNF313 antibody IHC staining of human spleen.
  • ICC - RNF114 / ZNF313 Antibody (aa1-228) ALS16904
    Immunofluorescence of paraformaldehyde-fixed HeLa using ZNF313 antibody at 1:200 dilution.
  • WB - RNF114 / ZNF313 Antibody (aa1-228) ALS16904
    Sample (30 ug of whole cell lysate). A: Hep G2 . 12 % SDS PAGE. RNF114 antibody diluted at 1:1000
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q9Y508
Other Accession 55905
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 25694 Da
Dilution ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:500 - 1:3000),
Additional Information
Gene ID 55905
Other Names RNF114, PSORS12, Ring finger protein 114, Zinc finger protein 313, ZNF228, ZNF313, Zinc finger protein 228
Target/Specificity Human RNF114
Reconstitution & Storage 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsRNF114 / ZNF313 Antibody (aa1-228) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF114
Synonyms ZNF228, ZNF313
Function E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis
Volume 50 µl
Citations (0)

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Background

E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.

References

Ma Y.-X.,et al.Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 35:230-237(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).

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$ 395.00
Cat# ALS16904
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