HRAS / H-Ras Antibody (aa111-189)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC |
---|---|
Primary Accession | P01112 |
Other Accession | 3265 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 21298 Da |
Dilution | ICC (1:100 - 1:1000), IHC-P (7.5 µg/ml), WB (1:500 - 1:3000), |
Gene ID | 3265 |
---|---|
Other Names | HRAS, C-H-RAS, C-has/bas p21 protein, C-ras-Ki-2 activated oncogene, C-HA-RAS1, CTLO, H-ras, H-RASIDX, GTP- and GDP-binding peptide B, GTPase HRas, H-Ras-1, HAMSV, HRAS1, K-RAS, Ha-Ras, Ha-Ras1 proto-oncoprotein, Transforming protein p21, N-ras, p21r ... |
Target/Specificity | Human HRAS |
Reconstitution & Storage | 0.1 M Tris-glycine, pH 7.0, 20% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
Precautions | HRAS / H-Ras Antibody (aa111-189) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HRAS |
---|---|
Synonyms | HRAS1 |
Function | Involved in the activation of Ras protein signal transduction (PubMed:22821884). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151). |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus membrane; Lipid-anchor. Note=The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity). Shuttles between the plasma membrane and the Golgi apparatus. |
Tissue Location | Widely expressed.. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
References
Capon D.J.,et al.Nature 302:33-37(1983).
Reddy E.P.,et al.Science 220:1061-1063(1983).
Sekiya T.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:4771-4775(1984).
Guil S.,et al.Cancer Res. 63:5178-5187(2003).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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