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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LTA / TNF Beta Antibody (aa31-80)   

LTA / TNF Beta Antibody (aa31-80)

Rabbit Polyclonal Antibody

     
  • IHC - LTA / TNF Beta Antibody (aa31-80) ALS16922
    Anti-LTA / TNF Beta antibody IHC staining of human kidney.
  • WB - LTA / TNF Beta Antibody (aa31-80) ALS16922
    Western blot of TNF- (H66) pAb in extracts from COS-7cells.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P01374
Other Accession 4049
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 22297 Da
Dilution IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 4049
Other Names LTA, Lymphotoxin-alpha, LT-alpha, TNFSF1, TNF-beta, TNFB, Tumor necrosis factor beta, LT, TNF Beta
Target/Specificity Human TNF Beta
Reconstitution & Storage PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsLTA / TNF Beta Antibody (aa31-80) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTA
Synonyms TNFB, TNFSF1
Function Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Cellular Location Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated
Volume 50 µl
Research Areas
Citations (0)

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Background

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.

References

Nedospasov S.A.,et al.Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986).
Nedwin G.E.,et al.J. Cell. Biochem. 29:171-181(1985).
Kobayashi Y.,et al.J. Biochem. 100:727-733(1986).
Gray P.W.,et al.Nature 312:721-724(1984).
Matsuyama N.,et al.FEBS Lett. 302:141-144(1992).

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$ 395.00
Cat# ALS16922
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