|Application ||WB, IHC-P, ICC|
|Calculated MW||36068 Da|
|Dilution||ICC (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:5000 - 1:20000),|
|Other Names||DECR1, 2, 4-dienoyl-coa reductase, 4-enoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase, DECR, NADPH, SDR18C1|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||DECR1 Antibody (aa1-335) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.|
|Tissue Location||Heart = liver = pancreas > kidney >> skeletal muscle = lung.|
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Provided below are standard protocols that you may find useful for product applications.
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.
Koivuranta K.T.,et al.Biochem. J. 304:787-792(1994).
Ding J.H.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Helander H.M.,et al.Genomics 46:112-119(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
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