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Complement C1s Antibody (clone 2D11)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, Flo |
|---|---|
| Primary Accession | P09871 |
| Other Accession | 716 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 2D11 |
| Calculated MW | 76684 Da |
| Dilution | Flo (1:100), IHC-P (10 µg/ml), WB (1:2000), |
| Gene ID | 716 |
|---|---|
| Other Names | C1S, C1 esterase, ComplementC1S, Complement 1s, Complement C1s subcomponent |
| Target/Specificity | Human ComplementC1S |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | Complement C1s Antibody (clone 2D11) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C1S |
|---|---|
| Function | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
References
McKinnon C.M.,et al.Eur. J. Biochem. 169:547-553(1987).
Tosi M.,et al.Biochemistry 26:8516-8524(1987).
Kusumoto H.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7307-7311(1988).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Endo Y.,et al.J. Immunol. 161:4924-4930(1998).
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