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APLNR/ Apelin Receptor / APJ Antibody (aa132-181)

Rabbit Polyclonal Antibody

     
  • IHC - APLNR/ Apelin Receptor / APJ Antibody (aa132-181) ALS16956
    Anti-APLNR/ Apelin Receptor / APJ antibody IHC staining of human small intestine.
  • IF - APLNR/ Apelin Receptor / APJ Antibody (aa132-181) ALS16956
    Immunofluorescence analysis of MCF7 cells, using AGTRL1 Antibody.
  • WB - APLNR/ Apelin Receptor / APJ Antibody (aa132-181) ALS16956
    Western blot of the lysates from HT-29 cells using AGTRL1 antibody.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P35414
Other Accession 187
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 42660 Da
Dilution ELISA (1:10000), IF (1:100 - 1:500), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 187
Other Names APLNR, AGTRL1, Angiotensin receptor-like 1, Angiotensin II receptor-like 1, Apelin receptor, APJ, APJ (apelin) receptor, APJR, G protein-coupled receptor APJ, HG11 orphan receptor, HG11, APJ receptor, G-protein coupled receptor APJ
Target/Specificity AGTRL1 antibody detects endogenous levels of AGTRL1.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsAPLNR/ Apelin Receptor / APJ Antibody (aa132-181) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APLNR
Synonyms AGTRL1, APJ
Function Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

References

O'Dowd B.F.,et al.Gene 136:355-360(1993).
Eggerickx D.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16956
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