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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Complement C3 Antibody (aa1580-1592)   

Complement C3 Antibody (aa1580-1592)

Goat Polyclonal Antibody

     
  • IHC - Complement C3 Antibody (aa1580-1592) ALS16963
    Anti-Complement C3 antibody IHC staining of human placenta.
  • IHC - Complement C3 Antibody (aa1580-1592) ALS16963
    Anti-Complement C3 antibody IHC staining of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P01024
Other Accession 718
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 187148 Da
Dilution ELISA (1:128000), IHC-P (5 µg/ml),
Additional Information
Gene ID 718
Other Names C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3
Target/Specificity Human Complement C3. This antibody is expected to recognize the C3 alpha chain, C3b alpha chain and the C3c alpha chain fragment 2.
Reconstitution & Storage Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsComplement C3 Antibody (aa1580-1592) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C3
Synonyms CPAMD1
Function C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation.
Cellular Location Secreted.
Tissue Location Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods
Research Areas
Citations (0)

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Background

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation.

References

de Bruijn M.H.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:708-712(1985).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Baldo A.,et al.J. Clin. Invest. 92:1543-1547(1993).
Hugli T.E.,et al.J. Biol. Chem. 250:8293-8301(1975).
Oxvig C.,et al.J. Biol. Chem. 270:13645-13651(1995).

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$ 395.00
Cat# ALS16963
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