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MKNK1 / MNK1 Antibody (aa216-265)

Rabbit Polyclonal Antibody

     
  • IHC - MKNK1 / MNK1 Antibody (aa216-265) ALS16971
    Anti-MKNK1 / MNK1 antibody IHC staining of human uterus.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BUB5
Other Accession 8569
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 51342 Da
Dilution ELISA (1:5000 - 1:40000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 8569
Other Names MKNK1, MNK1, MAPK-Interacting Kinase 1
Target/Specificity MNK1 (Ab-250) Antibody detects endogenous levels of total MNK1 protein.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsMKNK1 / MNK1 Antibody (aa216-265) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MKNK1
Synonyms MNK1
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap.
Cellular Location [Isoform 2]: Cytoplasm.
Tissue Location Ubiquitous..
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

References

Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16971
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