|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||51342 Da|
|Dilution||ELISA (1:5000 - 1:40000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),|
|Other Names||MKNK1, MNK1, MAPK-Interacting Kinase 1|
|Target/Specificity||MNK1 (Ab-250) Antibody detects endogenous levels of total MNK1 protein.|
|Reconstitution & Storage||PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.|
|Precautions||MKNK1 / MNK1 Antibody (aa216-265) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.|
|Cellular Location||Isoform 2: Cytoplasm.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
If you have any additional inquiries please email technical services at email@example.com.