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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RNF125 Antibody (aa131-180)   

RNF125 Antibody (aa131-180)

Rabbit Polyclonal Antibody

     
  • IHC - RNF125 Antibody (aa131-180) ALS16976
    Anti-RNF125 antibody IHC staining of human thymus.
  • IHC - RNF125 Antibody (aa131-180) ALS16976
    Anti-RNF125 antibody IHC staining of human small intestine.
  • WB - RNF125 Antibody (aa131-180) ALS16976
    Western blot of extracts from K562/HT-29 cells, using RNF125 Antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96EQ8
Other Accession 54941
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 26454 Da
Dilution ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 54941
Other Names RNF125, RING finger protein 125, TRAC-1, TRAC1
Target/Specificity RNF125 Antibody detects endogenous levels of total RNF125 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsRNF125 Antibody (aa131-180) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF125
Function E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.
Tissue Location Predominantly expressed in lymphoid tissues, including bone marrow, spleen and thymus. Also weakly expressed in other tissues. Predominant in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells
Volume 50 µl
Research Areas
Citations (0)

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Background

E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Chu P.,et al.J. Biol. 2:21.1-21.16(2003).
Zhao H.,et al.J. Immunol. 174:5288-5297(2005).

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$ 395.00
Cat# ALS16976
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