|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||68564 Da|
|Dilution||ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),|
|Other Names||RDX, Radixin, DFNB24|
|Target/Specificity||RDX Antibody detects endogenous levels of total RDX protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||RDX / Radixin Antibody (aa142-191) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively|
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Provided below are standard protocols that you may find useful for product applications.
Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
Wilgenbus K.K.,et al.Genomics 16:199-206(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Khan S.Y.,et al.Hum. Mutat. 28:417-423(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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