|Application ||WB, IHC-P, E|
|Calculated MW||14502 Da|
|Dilution||ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000),|
|Other Names||INSL3, Insulin-like 3 (Leydig cell), Insulin-like 3, Ley-I-L, Leydig insulin-like peptide, Relaxin-like factor, RLNL, Tyrosine protein kinase jak3m, Relaxin-like factor b, Leydig insulin -like hormone|
|Target/Specificity||INSL3 antibody detects endogenous levels of INSL3.|
|Reconstitution & Storage||PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.|
|Precautions||INSL3 Antibody (aa19-68) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.|
|Tissue Location||Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast.|
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Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
Burkhardt E.,et al.Hum. Genet. 94:91-94(1994).
Burkhardt E.,et al.Genomics 20:13-19(1994).
Tashima L.S.,et al.J. Clin. Endocrinol. Metab. 80:707-710(1995).
Lim H.N.,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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