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SERTAD1 / TRIP-Br1 / SEI-1 Antibody (aa168-217)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9UHV2 |
| Other Accession | 29950 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 24704 Da |
| Dilution | ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 29950 |
|---|---|
| Other Names | SERTAD1, CDK4-binding protein p34SEI, SEI-1, SERTA domain containing 1, TRIP-Br1, CDK4-binding protein p34SEI1, SEI1 |
| Target/Specificity | SEI-1 antibody detects endogenous levels of SEI-1. |
| Reconstitution & Storage | PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C. |
| Precautions | SERTAD1 / TRIP-Br1 / SEI-1 Antibody (aa168-217) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERTAD1 |
|---|---|
| Synonyms | SEI1, TRIPBR1 |
| Function | Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
References
Sugimoto M.,et al.Genes Dev. 13:3027-3033(1999).
Hsu S.-I.,et al.EMBO J. 20:2273-2285(2001).
Cheong J.K.,et al.J. Biol. Chem. 283:11661-11676(2008).
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