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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARG2 / Arginase 2 Antibody (aa305-354)   

ARG2 / Arginase 2 Antibody (aa305-354)

Rabbit Polyclonal Antibody

     
  • IHC - ARG2 / Arginase 2 Antibody (aa305-354) ALS16995
    Anti-Arginase II / ARG2 antibody IHC staining of human prostate.
  • WB - ARG2 / Arginase 2 Antibody (aa305-354) ALS16995
    Western blot of the lysates from HeLa cells using ARG2 antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P78540
Other Accession 384
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38578 Da
Dilution ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 384
Other Names ARG2, Arginase II, Kidney arginase, Nonhepatic arginase, Kidney-type arginase, L-arginine ureahydrolase, Type II arginase, Arginase 2, Arginase, type II, Arginase-2, mitochondrial, L-arginine amidinohydrolase, Non-hepatic arginase
Target/Specificity ARG2 Antibodyantibody detects endogenous levels of ARG2.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsARG2 / Arginase 2 Antibody (aa305-354) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARG2
Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Cellular Location Mitochondrion.
Tissue Location Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas
Volume 50 µl
Research Areas
Citations (0)

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Background

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

References

Gotoh T.,et al.FEBS Lett. 395:119-122(1996).
Vockley J.G.,et al.Genomics 38:118-123(1996).
Morris S.M. Jr.,et al.Gene 193:157-161(1997).
Lee Y.T.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16995
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