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SLC22A5 / OCTN2 Antibody (aa282-331)

Rabbit Polyclonal Antibody

     
  • IHC - SLC22A5 / OCTN2 Antibody (aa282-331) ALS16997
    Anti-SLC22A5 / OCTN2 antibody IHC staining of human heart.
  • WB - SLC22A5 / OCTN2 Antibody (aa282-331) ALS16997
    Western blot of the lysates from HeLa cells using SLC22A5 antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O76082
Other Accession 6584
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 62752 Da
Dilution ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 6584
Other Names SLC22A5, CDSP, OCTN2VT, OCTN2, UST2
Target/Specificity SLC22A5 Antibodyantibody detects endogenous levels of SLC22A5.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsSLC22A5 / OCTN2 Antibody (aa282-331) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC22A5
Synonyms OCTN2
Function Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells
Volume 50 µl
Research Areas
Citations (0)

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Background

Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3.

References

Wu X.,et al.Biochem. Biophys. Res. Commun. 246:589-595(1998).
Tamai I.,et al.J. Biol. Chem. 273:20378-20382(1998).
Nezu J.,et al.Nat. Genet. 21:91-94(1999).
Maekawa S.,et al.Biochim. Biophys. Acta 1773:1000-1006(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16997
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