TNFRSF19L / RELT Antibody (aa361-410)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q969Z4 |
Other Accession | 84957 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 46092 Da |
Dilution | ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000), |
Gene ID | 84957 |
---|---|
Other Names | RELT, TRLT, TNFRSF19L |
Target/Specificity | RELT Antibodyantibody detects endogenous levels of RELT. |
Reconstitution & Storage | PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C. |
Precautions | TNFRSF19L / RELT Antibody (aa361-410) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RELT |
---|---|
Synonyms | TNFRSF19L |
Function | May play a role in apoptosis (PubMed:28688764, PubMed:19969290). Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed (PubMed:16530727). Involved in dental enamel formation (PubMed:30506946). |
Cellular Location | Cell membrane; Single-pass type I membrane protein Cytoplasm. Cytoplasm, perinuclear region |
Tissue Location | Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mediates activation of NF-kappa-B. May play a role in T- cell activation.
References
Sica G.L.,et al.Blood 97:2702-2707(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Jikuya H.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Cusick J.K.,et al.Biochem. Biophys. Res. Commun. 340:535-543(2006).
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