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POU4F3 / BRN3C Antibody (aa266-295)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q15319 |
| Other Accession | 5459 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37052 Da |
| Dilution | IHC-P (2.5 µg/ml), WB (1:1000), |
| Gene ID | 5459 |
|---|---|
| Other Names | POU4F3, Brain-3C, BRN3C, POU class 4 homeobox 3, Brn-3C, DFNA15 |
| Target/Specificity | Human POU4F3 / BRN3C |
| Reconstitution & Storage | PBS, 0.09% sodium azide. Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | POU4F3 / BRN3C Antibody (aa266-295) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POU4F3 |
|---|---|
| Synonyms | BRN3C |
| Function | Acts as a transcriptional activator (PubMed:18228599). Acts by binding to sequences related to the consensus octamer motif 5'- ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity). |
| Cellular Location | Nucleus. Cytoplasm Note=Preferentially localized in the nucleus |
| Tissue Location | Brain. Seems to be specific to the retina. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in determining or maintaining the identities of a small subset of visual system neurons.
References
Xiang M.,et al.J. Neurosci. 15:4762-4785(1995).
Vahava O.,et al.Science 279:1950-1954(1998).
Collin R.W.J.,et al.Hum. Mutat. 29:545-554(2008).
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