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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   PDGF-AA Antibody (aa133-146)   

PDGF-AA Antibody (aa133-146)

Rabbit Polyclonal Antibody

     
  • IHC - PDGF-AA Antibody (aa133-146) ALS17020
    Human Small Intestine, Muscularis Propria: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P04085
Other Accession 5154
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 24043 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 5154
Other Names PDGFA, PDGF-A, PDGF A-chain, PDGF subunit A, PDGF-1, PDGF1
Target/Specificity Human PDGFA / PDGF-A
Reconstitution & Storage 0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsPDGF-AA Antibody (aa133-146) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDGFA
Synonyms PDGF1
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity).
Cellular Location Secreted. Note=Released by platelets upon wounding
Volume 50 µl
Research Areas
Citations (0)

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Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity).

References

Bonthron D.T.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1492-1496(1988).
Rorsman F.,et al.Mol. Cell. Biol. 8:571-577(1988).
Betsholtz C.,et al.Nature 320:695-699(1986).
Hoppe J.,et al.FEBS Lett. 223:243-246(1987).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).

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$ 395.00
Cat# ALS17020
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