|Application ||WB, IHC-P|
|Calculated MW||25387 Da|
|Dilution||IHC-P (10 µg/ml),|
|Other Names||APCS, 9.5S alpha-1-glycoprotein, Amyloid P component, serum, Pentaxin-related, PTX2, Serum Amyloid P, Serum amyloid P-component, SAP|
|Target/Specificity||Human APCS / Serum Amyloid P / SAP|
|Reconstitution & Storage||PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||APCS / Serum Amyloid P / SAP Antibody (aa1-223) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.|
|Tissue Location||Found in serum and urine.|
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Provided below are standard protocols that you may find useful for product applications.
Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Mantzouranis E.C.,et al.J. Biol. Chem. 260:7752-7756(1985).
Ohnishi S.,et al.J. Biochem. 100:849-858(1986).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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