|Application ||WB, IHC-P|
|Calculated MW||25387 Da|
|Dilution||IHC-P (10 µg/ml),|
|Other Names||APCS, 9.5S alpha-1-glycoprotein, Amyloid P component, serum, Pentaxin-related, PTX2, Serum Amyloid P, Serum amyloid P-component, SAP|
|Target/Specificity||Human APCS / Serum Amyloid P / SAP|
|Reconstitution & Storage||PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||APCS / Serum Amyloid P / SAP Antibody (aa1-223) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.|
|Tissue Location||Found in serum and urine.|
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Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Mantzouranis E.C.,et al.J. Biol. Chem. 260:7752-7756(1985).
Ohnishi S.,et al.J. Biochem. 100:849-858(1986).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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