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CNTNAP1 / CASPR / p190 Antibody (aa926-1190)

Rabbit Polyclonal Antibody

     
  • IHC - CNTNAP1 / CASPR / p190 Antibody (aa926-1190) ALS17030
    Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • WB - CNTNAP1 / CASPR / p190 Antibody (aa926-1190) ALS17030
    Western blot of recombinant CNTNAP1 / CASPR / p190.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P78357
Other Accession 8506
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 156267 Da
Dilution ELISA (1:100 - 1:200), IHC-P (1:100), WB (1:100 - 1:400),
Additional Information
Gene ID 8506
Other Names CNTNAP1, CASPR, Caspr1, Contactin associated protein 1, CNTNAP, Contactin-associated protein 1, Neurexin IV, Neurexin-4, Neurexin 4, NRXN4, p190
Target/Specificity Human CNTNAP1 / CASPR / p190
Reconstitution & Storage PBS, pH 7.4, 0.02% sodium azide, 50% glycerol. Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
PrecautionsCNTNAP1 / CASPR / p190 Antibody (aa926-1190) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNTNAP1
Synonyms CASPR, NRXN4
Function Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis
Research Areas
Citations (0)

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Background

Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.

References

Peles E.,et al.EMBO J. 16:978-988(1997).

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$ 395.00
Cat# ALS17030
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