|Application ||WB, IHC-P, Flo|
|Calculated MW||19300 Da|
|Dilution||Flo (1:10 - 1:50), IHC-P (5 µg/ml), WB (1:1000),|
|Other Names||PPP3R1, CALNB1, CNA2, Calcineurin B, type I (19kDa), Calcineurin subunit B type 1, CNB, Calcineurin b, CNB1|
|Target/Specificity||Human PPP3R1 / Calcineurin B|
|Reconstitution & Storage||PBS, 0.09% sodium azide. Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||PPP3R1 / Calcineurin B Antibody (aa7-37) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.|
|Cellular Location||Cytoplasm, cytosol. Cell membrane. Cell membrane, sarcolemma. Membrane; Lipid-anchor. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocytes hypertrophy.|
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Provided below are standard protocols that you may find useful for product applications.
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Guerini D.,et al.DNA 8:675-682(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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