PPP3R1 / Calcineurin B Antibody (aa7-37)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, Flo |
---|---|
Primary Accession | P63098 |
Other Accession | 5534 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 19300 Da |
Dilution | Flo (1:10 - 1:50), IHC-P (5 µg/ml), WB (1:1000), |
Gene ID | 5534 |
---|---|
Other Names | PPP3R1, CALNB1, CNA2, Calcineurin B, type I (19kDa), Calcineurin subunit B type 1, CNB, Calcineurin b, CNB1 |
Target/Specificity | Human PPP3R1 / Calcineurin B |
Reconstitution & Storage | PBS, 0.09% sodium azide. Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | PPP3R1 / Calcineurin B Antibody (aa7-37) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP3R1 |
---|---|
Synonyms | CNA2, CNB |
Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000250|UniProtKB:Q63810}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q63810}. Cell membrane; Lipid-anchor. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. {ECO:0000250|UniProtKB:Q63810} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
References
Guerini D.,et al.DNA 8:675-682(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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