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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   BDNF Antibody   

BDNF Antibody

Chicken Polyclonal Antibody

     
  • IHC - BDNF Antibody ALS17063
    Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - BDNF Antibody ALS17063
    Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP, IHC-Fr
Primary Accession P23560
Other Accession 627
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Isotype IgY
Calculated MW 27818 Da
Dilution IHC-P (1:100), WB (1:500 - 1:1000), WB (1:500 - 1:1000),
Additional Information
Gene ID 627
Other Names BDNF, ANON2, Abrineurin, BULN2, Neurotrophin
Target/Specificity Reacts with proBDNF. Does not recognize mature BDNF isoforms
Reconstitution & Storage PBS. Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
PrecautionsBDNF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BDNF
Function During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Cellular Location Secreted.
Tissue Location Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta
Volume 50 µl
Research Areas
Citations (0)

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Background

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

References

Jones K.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8060-8064(1990).
Maisonpierre P.C.,et al.Genomics 10:558-568(1991).
Shintani A.,et al.Biochem. Biophys. Res. Commun. 182:325-332(1992).
Liu Q.-R.,et al.Am. J. Med. Genet. B Neuropsychiatr. Genet. 134:93-103(2005).
Pruunsild P.,et al.Genomics 90:397-406(2007).

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$ 395.00
Cat# ALS17063
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