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SRR / Serine Racemase Antibody (aa131-340)

Rabbit Polyclonal Antibody

     
  • IHC - SRR / Serine Racemase Antibody (aa131-340) ALS17065
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - SRR / Serine Racemase Antibody (aa131-340) ALS17065
    Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q9GZT4
Other Accession 63826
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 36566 Da
Dilution IHC-P (5 µg/ml),
Additional Information
Gene ID 63826
Other Names SRR, D-serine dehydratase, ISO1, L-serine ammonia-lyase, L-serine dehydratase, ILV1, Serine racemase, D-serine ammonia-lyase
Target/Specificity Human SRR / Serine Racemase
Reconstitution & Storage 0.1 M Tris-glycine, pH 7, 20% Glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsSRR / Serine Racemase Antibody (aa131-340) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRR
Function Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Tissue Location Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver
Volume 50 µl
Research Areas
Citations (0)

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Background

Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.

References

De Miranda J.,et al.Gene 256:183-188(2000).
Xia M.,et al.Brain Res. Mol. Brain Res. 125:96-104(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS17065
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