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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DCK / Deoxycytidine kinase Antibody   

DCK / Deoxycytidine kinase Antibody

Rabbit Polyclonal Antibody

     
  • IHC - DCK / Deoxycytidine kinase Antibody ALS17078
    Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IF - DCK / Deoxycytidine kinase Antibody ALS17078
    Immunofluorescence analysis of MCF7 cell using DCK antibody. Blue: DAPI for nuclear staining.
  • WB - DCK / Deoxycytidine kinase Antibody ALS17078
    Western blot analysis of extracts of various cell lines, using DCK antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P27707
Other Accession 1633
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 30519 Da
Dilution IF (1:50 - 1:200), IHC-P (5 µg/ml), WB (1:500 - 1:2000),
Additional Information
Gene ID 1633
Other Names DCK, Deoxynucleoside kinase, Deoxycytidine kinase
Target/Specificity Human DCK / Deoxycytidine kinase
Reconstitution & Storage PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
PrecautionsDCK / Deoxycytidine kinase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCK
Function Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Cellular Location Nucleus.
Volume 50 µl
Research Areas
Citations (0)

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Background

Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.

References

Chottiner E.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:1531-1535(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS17078
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