|Application ||WB, IHC-P, IF, ICC, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||59226 Da|
|Dilution||ICC (2.5 µg/ml), IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||OASL, 2-5-OAS-related protein, 2-5-OAS-RP, p59-OASL, p59OASL, TR-interacting protein 14, TRIP-14, TRIP14, OASLd, p59 OASL|
|Target/Specificity||OASL antibody is human, mouse and rat reactive.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||OASL Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.|
|Cellular Location||Isoform p56: Nucleus, nucleolus. Cytoplasm.|
|Tissue Location||Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Hartmann R.,et al.Nucleic Acids Res. 26:4121-4127(1998).
Rebouillat D.,et al.Eur. J. Biochem. 257:319-330(1998).
Guo X.,et al.Int. J. Biochem. Cell Biol. 44:1133-1138(2012).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.