|Application ||WB, IHC-P|
|Reactivity||Mouse, Rat, Bovine, Dog|
|Calculated MW||165283 Da|
|Dilution||IHC-P (1:100), WB (1:1000),|
|Other Names||GRIN2A, EPND, HNR2A, GluN2A, GluR epsilon 1, NMDA receptor 2A, NMDAR2A, NR2A, NMDA receptor subtype 2A|
|Target/Specificity||Specific for the ~180k NR2A subunit of the NMDA receptor|
|Reconstitution & Storage||10 mM HEPES, pH 7.5, 150 mM sodium chloride, 100 ug per ml BSA, 50% glycerol. Long term: -20°C; Short term: -20°C|
|Precautions||GRIN2A / NMDAR2A / NR2A Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Foldes R.L.,et al.Biochim. Biophys. Acta 1223:155-159(1994).
Hess S.D.,et al.J. Pharmacol. Exp. Ther. 278:808-816(1996).
Martin J.,et al.Nature 432:988-994(2004).
Endele S.,et al.Nat. Genet. 42:1021-1026(2010).
Wei X.,et al.Nat. Genet. 43:442-446(2011).
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