|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||27296 Da|
|Dilution||IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||PRRX1, AGOTC, Homeobox protein PHOX1, Paired related homeobox 1, PHOX1, PRX1, Paired mesoderm homeo box 1, PRX-1, PMX1|
|Target/Specificity||PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist; this antibody will detect both isoforms.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PRX-1 / PRRX1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (By similarity).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Gregory S.G.,et al.Nature 441:315-321(2006).
Grueneberg D.A.,et al.Science 257:1089-1095(1992).
Sergi C.,et al.Clin. Genet. 79:293-295(2011).
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