SOX4 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q06945 |
Other Accession | 6659 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 47263 Da |
Dilution | IHC-P (10 µg/ml), WB (1 - 2 µg/ml), WB (1 - 2 µg/ml), |
Gene ID | 6659 |
---|---|
Other Names | SOX4, EVI16, SRY-related HMG-box gene 4, Transcription factor SOX-4 |
Target/Specificity | SOX4 antibody is human, mouse and rat reactive. |
Reconstitution & Storage | PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | SOX4 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SOX4 {ECO:0000303|PubMed:8268656, ECO:0000312|HGNC:HGNC:11200} |
---|---|
Function | Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:30661772). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity). Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed:26291311). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:16631117} |
Tissue Location | Testis, brain, and heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
References
Farr C.J.,et al.Mamm. Genome 4:577-584(1993).
Mungall A.J.,et al.Nature 425:805-811(2003).
Denny P.,et al.Nucleic Acids Res. 20:2887-2887(1992).
Pan X.,et al.Biochem. Biophys. Res. Commun. 344:727-734(2006).
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