|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||38143 Da|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||KCNK1, DPK, HOHO, KCNO1, HOHO1, Potassium channel KCNO1, TWIK1, TWIK-1, K2P1, K2p1.1|
|Target/Specificity||KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TWIK1 / KCNK1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||HOHO1, KCNO1, TWIK1|
|Function||Weakly inward rectifying potassium channel that contributes to the regulation of the resting membrane potential.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney (PubMed:8605869).|
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Provided below are standard protocols that you may find useful for product applications.
Weakly inward rectifying potassium channel.
Lesage F.,et al.EMBO J. 15:1004-1011(1996).
Goldstein S.A.N.,et al.J. Mol. Med. 76:13-20(1998).
Orias M.,et al.Am. J. Physiol. 273:F663-F666(1997).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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