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>   home   >   Products   >   Primary Antibodies   >   KLF17 Antibody (C-Terminus)   

KLF17 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - KLF17 Antibody (C-Terminus) ALS17119
    Immunohistochemistry of KLF17 in mouse liver tissue with KLG17 antibody at 5 ug/ml.
  • IHC - KLF17 Antibody (C-Terminus) ALS17119
    Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - KLF17 Antibody (C-Terminus) ALS17119
    Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q5JT82
Other Accession 128209
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 42577 Da
Dilution IHC-P (10 µg/ml), WB (1 - 2 µg/ml),
Additional Information
Gene ID 128209
Other Names KLF17, Kruppel-like factor 17, Novel zinc-finger protein, Zfp393, ZNF393, RP4-675G8.1, Zinc finger protein 393, Krueppel-like factor 17
Target/Specificity KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist; this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins.
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsKLF17 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLF17
Synonyms ZNF393
Function Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).
Cellular Location Nucleus.
Citations (0)

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Background

Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
van Vliet J.,et al.Genomics 87:474-482(2006).

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$ 395.00
Cat# ALS17119
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